Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.R278R

OPRM1

1,057 papers

RefSeq Summary

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta...

Pfam Domains

7tm_1aa 87–338UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

opioid receptor mu 1

HGNC Alias Symbols

MOR1; MOP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000914.5
p.R278R
c.832C>A
Surrounding Variants
1 paper
NM_000914.5
p.L277F
c.829C>T
1 paper
NM_000914.5
p.N276Y
c.826A>T
1 paper
NM_000914.5
p.D274E
c.822C>A
7 papers
NM_000914.5
p.D274N
c.820G>A
1 paper
NM_000914.5
p.R282K
c.845G>A
1 paper
NM_000914.5
p.K273insFs
c.817dupA
1 paper
NM_000914.5
p.G269D
c.806G>A
1 paper
NM_000914.5
p.V287V
c.861G>C
29 papers
NM_000914.5
p.S268P
c.802T>C
1 paper
NM_001145279.4
p.L360fs
c.1078_1079fs
1 paper
NM_001145279.4
p.L360delFs
c.1078delC
1 paper
NM_000914.5
p.V290M
c.868G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."