Varaico: Literature-Extracted Genetic Variants

PARP2

131 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain whi...

Pfam Domains

WGRaa 115–195UCSCWGR domain

PARP_regaa 232–362UCSCPoly(ADP-ribose) polymerase, regulatory domain

PARPaa 376–577UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase 2

HGNC Previous Symbol

ADPRTL2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 79 variants

9 papers

NM_001042618.2

p.E545A

c.1634A>C

5 papers

NM_001042618.2

p.R15G

c.43A>G

3 papers

NM_001042618.2

p.K37R

c.110A>G

3 papers

NM_001042618.2

p.Y188F

c.563A>T

2 papers

NM_001042618.2

p.N24fs

c.70_71fs

2 papers

NM_001042618.2

p.I329insFs

c.985_986insA

2 papers

NM_001042618.2

p.S370insFs

c.1109_1110insT

1 paper

NM_001042618.2

p.A2V

c.5C>T

1 paper

NM_001042618.2

p.R5L

c.14G>T

1 paper

NM_001042618.2

p.R6G

c.16C>G

1 paper

NM_001042618.2

p.G11S

c.31G>A

1 paper

NM_001042618.2

p.G12delFs

c.34delG