Varaico: Literature-Extracted Genetic Variants

POLB

394 papers

RefSeq Summary

The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cyt...

Pfam Domains

HHH_8aa 11–82UCSCHelix-hairpin-helix domain

DNA_pol_lambd_faa 98–147UCSCFingers domain of DNA polymerase lambda

DNA_pol_B_palmaa 149–262UCSCDNA polymerase beta palm

DNA_pol_B_thumbaa 268–334UCSCDNA polymerase beta thumb

Gene Aliases

HGNC Name

DNA polymerase beta

HGNC Previous Names

polymerase (DNA directed), beta; polymerase (DNA) beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

41 papers

NM_002690.3

p.E295K

c.883G>A

Surrounding Variants

5 papers

NM_002690.3

p.E295A

c.884A>C

1 paper

NM_002690.3

p.N294D

c.880A>G

1 paper

NM_002690.3

p.Y296D

c.886T>G

1 paper

NM_002690.3

p.T297I

c.890C>T

1 paper

NM_002690.3

p.T292I

c.875C>T

4 papers

NM_002690.3

p.T292A

c.874A>G

1 paper

NM_002690.3

p.F291L

c.873C>A

1 paper

NM_002690.3

p.F291L

c.873C>G

4 papers

NM_002690.3

p.I298T

c.893T>C

1 paper

NM_002690.3

p.R299S

c.895C>A

1 paper

NM_002690.3

p.R299C

c.895C>T

1 paper

NM_002690.3

p.F291L

c.871T>C