Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

1–12 of 372 variants

55 papers

NM_000963.4

p.I399V

c.1195A>G

31 papers

NM_000963.4

p.V511A

c.1532T>C

25 papers

NM_000963.4

p.V430V

c.1290A>G

15 papers

NM_000963.4

p.G587R

c.1759G>A

13 papers

NM_000963.4

p.G279G

c.837T>C

9 papers

NM_000963.4

p.G587R

c.1759G>C

7 papers

NM_000963.4

p.C54W

c.162C>G

7 papers

NM_000963.4

p.R228H

c.683G>A

7 papers

NM_000963.4

p.W309S

c.926G>C

7 papers

NM_000963.4

p.N361S

c.1082A>G

6 papers

NM_000963.4

p.T17I

c.50C>T

6 papers

NM_000963.4

p.P57A

c.169C>G