Varaico: Literature-Extracted Genetic Variants

PTK6

95 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epit...

Pfam Domains

SH3_1aa 14–64UCSCSH3 domain

SH2aa 78–155UCSCSH2 domain

PK_Tyr_Ser-Thraa 191–441UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

protein tyrosine kinase 6

HGNC Previous Name

PTK6 protein tyrosine kinase 6

Papers

RefSeq ID

Protein change

DNA change

1–12 of 95 variants

9 papers

NM_005975.4

p.K219M

c.656A>T

7 papers

NM_005975.4

p.Y447F

c.1340A>T

3 papers

NM_005975.4

p.P450L

c.1349C>T

2 papers

NM_005975.4

p.L16F

c.46C>T

2 papers

NM_005975.4

p.P175A

c.523C>G

2 papers

NM_005975.4

p.P177A

c.529C>G

2 papers

NM_005975.4

p.P179A

c.535C>G

2 papers

NM_005975.4

p.P187A

c.559C>G

2 papers

NM_005975.4

p.W210*

c.629G>A

2 papers

NM_005975.4

p.W210*

c.630G>A

2 papers

NM_005975.4

p.V253M

c.757G>A

2 papers

NM_005975.4

p.D312N

c.934G>A