Varaico: Literature-Extracted Genetic Variants

RXRA

248 papers

RefSeq Summary

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. Th...

Pfam Domains

Nuc_recep-AF1aa 17–127UCSCNuclear/hormone receptor activator site AF-1

zf-C4aa 133–202UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 256–442UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

retinoid X receptor alpha

HGNC Alias Symbols

NR2B1; RXRalpha; RXR-alpha

Papers

RefSeq ID

Protein change

DNA change

1–12 of 205 variants

31 papers

NM_002957.6

p.S427F

c.1280C>T

11 papers

NM_002957.6

p.S427Y

c.1280C>A

4 papers

NM_002957.6

p.T23M

c.68C>T

4 papers

NM_002957.6

p.R316H

c.947G>A

3 papers

NM_002957.6

p.L111fs

c.331_332fs

3 papers

NM_002957.6

p.A121T

c.361G>A

3 papers

NM_002957.6

p.P231L

c.692C>T

3 papers

NM_002957.6

p.M254I

c.762G>A

2 papers

NM_002957.6

p.I41F

c.121A>T

2 papers

NM_002957.6

p.S76S

c.228C>A

2 papers

NM_002957.6

p.L111insFs

c.331dupC

2 papers

NM_002957.6

p.A226V

c.677C>T