Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.S131L

c.392C>T

Surrounding Variants

1 paper

NM_006446.5

p.S132L

c.395C>T

4 papers

NM_006446.5

p.N130H

c.388A>C

531 papers

NM_006446.5

p.N130D

c.388A>G

1 paper

NM_006446.5

p.N130Y

c.388A>T

1 paper

NM_006446.5

p.N134insFs

c.401dupA

1 paper

NM_006446.5

p.I129V

c.385A>G

1 paper

NM_006446.5

p.N134fs

c.400_401fs

4 papers

NM_006446.5

p.N128Y

c.382A>T

1 paper

NM_006446.5

p.T127S

c.380C>G

1 paper

NM_006446.5

p.T127S

c.379A>T

1 paper

NM_006446.5

p.E126K

c.376G>A

1 paper

NM_006446.5

p.S137L

c.410C>T