Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 855 variants

20 papers

NM_198291.3

p.E527K

c.1579G>A

15 papers

NM_198291.3

p.Q531*

c.1591C>T

9 papers

NM_198291.3

p.Y530F

c.1589A>T

8 papers

NM_198291.3

p.E457A

c.1370A>C

7 papers

NM_198291.3

p.A406A

c.1218G>C

5 papers

NM_198291.3

p.R391C

c.1171C>T

4 papers

NM_198291.3

p.A59T

c.175G>A

4 papers

NM_198291.3

p.P171L

c.512C>T

4 papers

NM_198291.3

p.V177M

c.529G>A

4 papers

NM_198291.3

p.T183M

c.548C>T

4 papers

NM_198291.3

p.T341M

c.1022C>T

4 papers

NM_198291.3

p.E381K

c.1141G>A