Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.K289R

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_198282.4
p.K289R
c.866A>G
Surrounding Variants
1 paper
NM_198282.4
p.C292S
c.874T>A
1 paper
NM_198282.4
p.C292S
c.875G>C
1 paper
NM_198282.4
p.E286A
c.857A>C
1 paper
NM_198282.4
p.E286K
c.856G>A
1 paper
NM_198282.4
p.L285P
c.854T>C
69 papers
NM_198282.4
p.R293Q
c.878G>A
1 paper
NM_198282.4
p.L285I
c.853C>A
34 papers
NM_198282.4
p.R284S
c.852G>T
34 papers
NM_198282.4
p.R284S
c.852G>C
9 papers
NM_198282.4
p.R284M
c.851G>T
5 papers
NM_198282.4
p.R284T
c.851G>C
2 papers
NM_198282.4
p.R284K
c.851G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."