Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.K48N

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.K48N
c.144G>T
Surrounding Variants
1 paper
NM_000455.5
p.K48N
c.144G>C
6 papers
NM_000455.5
p.K48R
c.143A>G
1 paper
NM_000455.5
p.K48_M51delFs
c.144_153del10
1 paper
NM_000455.5
p.Y49H
c.145T>C
9 papers
NM_000455.5
p.Y49D
c.145T>G
2 papers
NM_000455.5
p.Y49fs
c.145_146fs
2 papers
NM_000455.5
p.Y49fs
c.145_146fs
1 paper
NM_000455.5
p.Y49delFs
c.146_147delAC
5 papers
NM_000455.5
p.L50_D53del0
c.148_159del12
2 papers
NM_000455.5
p.K48fs
c.142_143fs
1 paper
NM_000455.5
p.K48_Y49ins4
c.142_146ins12
1 paper
NM_000455.5
p.K48Q
c.142A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."