Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

724 papers

NM_007375.4

p.M337V

c.1009A>G

Surrounding Variants

2 papers

NM_007375.4

p.M336V

c.1006A>G

1 paper

NM_007375.4

p.G338S

c.1012G>A

10 papers

NM_007375.4

p.G338A

c.1013G>C

1 paper

NM_007375.4

p.G335G

c.1005T>A

78 papers

NM_007375.4

p.G335D

c.1004G>A

15 papers

NM_007375.4

p.G335A

c.1004G>C

2 papers

NM_007375.4

p.G335V

c.1004G>T

1 paper

NM_007375.4

p.M339V

c.1015A>G

6 papers

NM_007375.4

p.G335S

c.1003G>A

1 paper

NM_007375.4

p.G335C

c.1003G>T

2 papers

NM_007375.4

p.M339I

c.1017G>A

1 paper

NM_007375.4

p.W334*

c.1001G>A