Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 121 variants

10 papers

NM_003141.4

p.R6S

c.16C>A

4 papers

NM_003141.4

p.R64Q

c.191G>A

3 papers

NM_003141.4

p.E12A

c.35A>C

3 papers

NM_003141.4

p.E13A

c.38A>C

3 papers

NM_003141.4

p.R57C

c.169C>T

3 papers

NM_003141.4

p.D355A

c.1064A>C

3 papers

NM_003141.4

p.F446I

c.1336T>A

2 papers

NM_003141.4

p.E38G

c.113A>G

2 papers

NM_003141.4

p.R57H

c.170G>A

2 papers

NM_003141.4

p.G89E

c.266G>A

2 papers

NM_003141.4

p.L110P

c.329T>C

2 papers

NM_003141.4

p.R234*

c.700C>T