Varaico: Literature-Extracted Genetic Variants

WNK3

144 papers

RefSeq Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved l...

Pfam Domains

Pkinaseaa 147–405UCSCProtein kinase domain

OSR1_Caa 426–489UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 743–819UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 3

HGNC Previous Symbol

PRKWNK3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020922.5

p.M301V

c.901A>G

Surrounding Variants

1 paper

NM_020922.5

p.L300S

c.899T>C

1 paper

NM_020922.5

p.R302H

c.905G>A

3 papers

NM_020922.5

p.L297F

c.891A>T

3 papers

NM_020922.5

p.L297F

c.891A>C

13 papers

NM_020922.5

p.D294A

c.881A>C

1 paper

NM_020922.5

p.V290L

c.868G>T

1 paper

NM_020922.5

p.V290L

c.868G>C

1 paper

NM_020922.5

p.T287N

c.860C>A

2 papers

NM_020922.5

p.D279N

c.835G>A

1 paper

NM_020922.5

p.P269_I271delFs

c.805_812del8

1 paper

NM_020922.5

p.L250delFs

c.748delA

1 paper

NM_020922.5

p.K240_R241delFs

c.720_723del4