Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 277 variants

768 papers

NM_005432.4

p.T241M

c.722C>T

43 papers

NM_005432.4

p.R81C

c.241C>T

24 papers

NM_005432.4

p.E45D

c.135G>C

22 papers

NM_005432.4

p.S326C

c.977C>G

14 papers

NM_005432.4

p.V187_D188Splc

c.562-14A>G

7 papers

NM_005432.4

p.D213N

c.637G>A

7 papers

NM_005432.4

p.R243H

c.728G>A

5 papers

NM_005432.4

p.R94H

c.281G>A

5 papers

NM_005432.4

p.R150C

c.448C>T

5 papers

NM_005432.4

p.T287A

c.859A>G

4 papers

NM_005432.4

p.A65Splc

c.194-571A>G

3 papers

NM_005432.4

p.M1L

c.1A>T