Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

31 papers

NM_001382430.1

p.Q61H

c.183G>C

Surrounding Variants

31 papers

NM_001382430.1

p.Q61H

c.183G>T

24 papers

NM_001382430.1

p.Q61L

c.182A>T

26 papers

NM_001382430.1

p.Q61R

c.182A>G

3 papers

NM_001382430.1

p.Q61P

c.182A>C

1 paper

NM_001382430.1

p.L62insFs

c.184dupC

1 paper

NM_001382430.1

p.L62R

c.185T>G

1 paper

NM_001382430.1

p.L62P

c.185T>C

2 papers

NM_001382430.1

p.Q61*

c.181C>T

4 papers

NM_001382430.1

p.Q61E

c.181C>G

27 papers

NM_001382430.1

p.Q61K

c.181C>A

1 paper

NM_001382430.1

p.L62L

c.186G>C

1 paper

NM_001382430.1

p.C60C

c.180C>T