Varaico: Literature-Extracted Genetic Variants

FTO

395 papers

RefSeq Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron ...

Pfam Domains

FTO_NTDaa 36–325UCSCFTO catalytic domain

FTO_CTDaa 329–498UCSCFTO C-terminal domain

Gene Aliases

HGNC Name

FTO alpha-ketoglutarate dependent dioxygenase

HGNC Alias Symbols

KIAA1752; MGC5149; ALKBH9; IFEX9

Papers

RefSeq ID

Protein change

DNA change

1–12 of 465 variants

49 papers

NM_001080432.3

p.R316Q

c.947G>A

18 papers

NM_001080432.3

p.R322Q

c.965G>A

14 papers

NM_001080432.3

p.A134T

c.400G>A

12 papers

NM_001080432.3

p.D233A

c.698A>C

11 papers

NM_001080432.3

p.T92T

c.276T>G

10 papers

NM_001080432.3

p.R96H

c.287G>A

9 papers

NM_001080432.3

p.K45I

c.134A>T

9 papers

NM_001080432.3

p.A163T

c.487G>A

8 papers

NM_001080432.3

p.A405V

c.1214C>T

7 papers

NM_001080432.3

p.G103D

c.308G>A

7 papers

NM_001080432.3

p.S319F

c.956C>T

6 papers

NM_001080432.3

p.P93R

c.278C>G