Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 197 variants

48 papers

NM_001619.5

p.K220R

c.659A>G

8 papers

NM_001619.5

p.D110A

c.329A>C

5 papers

NM_001619.5

p.D10A

c.29A>C

5 papers

NM_001619.5

p.D527A

c.1580A>C

5 papers

NM_001619.5

p.S670A

c.2008T>G

4 papers

NM_001619.5

p.V7A

c.20T>C

4 papers

NM_001619.5

p.S450delFs

c.1348_1349delAG

3 papers

NM_001619.5

p.D3A

c.8A>C

3 papers

NM_001619.5

p.A16V

c.47C>T

3 papers

NM_001619.5

p.L157F

c.469C>T

3 papers

NM_001619.5

p.H185_L186Splc

c.555+1G>A

3 papers

NM_001619.5

p.D481A

c.1442A>C