Varaico: Literature-Extracted Genetic Variants

Gene:IL4R

IL4R

559 papers

RefSeq Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can ...

Pfam Domains

IL4Ra_Naa 28–121UCSCInterleukin-4 receptor alpha chain, N-terminal

Gene Aliases

HGNC Name

interleukin 4 receptor

HGNC Alias Symbol

CD124

Papers
RefSeq ID
Protein change
DNA change
1–12 of 260 variants
195 papers
NM_000418.4
p.Q576R
c.1727A>G
88 papers
NM_000418.4
p.S503P
c.1507T>C
80 papers
NM_000418.4
p.I75V
c.223A>G
33 papers
NM_000418.4
p.E400A
c.1199A>C
29 papers
NM_000418.4
p.E375A
c.1124A>C
28 papers
NM_000418.4
p.C431R
c.1291T>C
17 papers
NM_000418.4
p.S752A
c.2254T>G
13 papers
NM_000418.4
p.S436L
c.1307C>T
8 papers
NM_000418.4
p.A82T
c.244G>A
8 papers
NM_000418.4
p.S786P
c.2356T>C
7 papers
NM_000418.4
p.G80R
c.238G>A
6 papers
NM_000418.4
p.E551G
c.1652A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."