Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

51 papers

NM_001127500.3

p.D1028N

c.3082G>A

NM_000245.4

p.D1010N

c.3028G>A

Surrounding Variants

66 papers

NM_000245.4

p.D1010H

c.3028G>C

NM_001127500.3

p.D1028H

c.3082G>C

30 papers

NM_000245.4

p.D1010Y

c.3028G>T

NM_001127500.3

p.D1028Y

c.3082G>T

2 papers

NM_000245.4

p.E1009D

c.3027A>C

2 papers

NM_001127500.3

p.E1027E

c.3081A>G

NM_000245.4

p.E1009E

c.3027A>G

2 papers

NM_000245.4

p.E1009D

c.3027A>T

3 papers

NM_000245.4

p.D1010delFs

c.3028delG

30 papers

NM_000245.4

p.D1010Splc

c.3028+1G>A

NM_001127500.3

p.D1028Splc

c.3082+1G>A

14 papers

NM_000245.4

p.D1010Splc

c.3028+1G>C

32 papers

NM_000245.4

p.D1010Splc

c.3028+1G>T

NM_001127500.3

p.D1028Splc

c.3082+1G>T

14 papers

NM_000245.4

p.D1010Splc

c.3028+2T>A

NM_001127500.3

p.D1028Splc

c.3082+2T>A

24 papers

NM_000245.4

p.D1010Splc

c.3028+2T>C

NM_001127500.3

p.D1028Splc

c.3082+2T>C

13 papers

NM_000245.4

p.D1010Splc

c.3028+2T>G