Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

1–12 of 132 variants

8 papers

NM_152649.4

p.Q48*

c.142C>T

7 papers

NM_152649.4

p.S132P

c.394T>C

6 papers

NM_152649.4

p.T357A

c.1069A>G

6 papers

NM_152649.4

p.S358A

c.1072T>G

4 papers

NM_152649.4

p.E19K

c.55G>A

4 papers

NM_152649.4

p.K26E

c.76A>G

4 papers

NM_152649.4

p.G316D

c.947G>A

4 papers

NM_152649.4

p.D369_R370delFs

c.1107_1110del4

3 papers

NM_152649.4

p.D107A

c.320A>C

3 papers

NM_152649.4

p.R146Q

c.437G>A

3 papers

NM_152649.4

p.D369fs

c.1105_1106fs

2 papers

NM_152649.4

p.K22E

c.64A>G