Varaico: Literature-Extracted Genetic Variants

SLC6A4

777 papers

RefSeq Summary

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and ...

Pfam Domains

5HT_transport_Naa 24–64UCSCSerotonin (5-HT) neurotransmitter transporter, N-terminus

SNFaa 79–600UCSCSodium:neurotransmitter symporter family

Gene Aliases

HGNC Name

solute carrier family 6 member 4

HGNC Previous Symbol

OCD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001045.6

p.T433M

c.1298C>T

Surrounding Variants

8 papers

NM_001045.6

p.L429L

c.1287G>A

2 papers

NM_001045.6

p.D437A

c.1310A>C

6 papers

NM_001045.6

p.S438T

c.1313G>C

17 papers

NM_001045.6

p.T439S

c.1315A>T

3 papers

NM_001045.6

p.T439A

c.1315A>G

2 papers

NM_001045.6

p.T439T

c.1317G>A

73 papers

NM_001045.6

p.I425V

c.1273A>G

23 papers

NM_001045.6

p.I425L

c.1273A>C

1 paper

NM_001045.6

p.F423C

c.1268T>G

1 paper

NM_001045.6

p.F422C

c.1265T>G

1 paper

NM_001045.6

p.T421I

c.1262C>T

1 paper

NM_001045.6

p.S420C

c.1259C>G