Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 362 variants

23 papers

NM_032271.3

p.R655Q

c.1964G>A

22 papers

NM_032271.3

p.N520S

c.1559A>G

18 papers

NM_032271.3

p.G536S

c.1606G>A

14 papers

NM_032271.3

p.K615E

c.1843A>G

14 papers

NM_032271.3

p.R641C

c.1921C>T

11 papers

NM_032271.3

p.R653Q

c.1958G>A

10 papers

NM_032271.3

p.R524W

c.1570C>T

10 papers

NM_032271.3

p.S561R

c.1681A>C

10 papers

NM_032271.3

p.S561R

c.1683C>A

10 papers

NM_032271.3

p.S561R

c.1683C>G

9 papers

NM_032271.3

p.H521R

c.1562A>G

8 papers

NM_032271.3

p.T391I

c.1172C>T