Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

1–12 of 406 variants

688 papers

NM_002542.6

p.S326C

c.977C>G

55 papers

NM_002542.6

p.R46Q

c.137G>A

46 papers

NM_002542.6

p.R154H

c.461G>A

35 papers

NM_002542.6

p.G308E

c.923G>A

30 papers

NM_002542.6

p.K249Q

c.745A>C

29 papers

NM_002542.6

p.R229Q

c.686G>A

22 papers

NM_002542.6

p.A288V

c.863C>T

17 papers

NM_002542.6

p.A53T

c.157G>A

16 papers

NM_002542.6

p.A85S

c.253G>T

12 papers

NM_002542.6

p.R131Q

c.392G>A

11 papers

NM_002542.6

p.T105T

c.315C>G

10 papers

NM_002542.6

p.G12E

c.35G>A