Varaico: Literature-Extracted Genetic Variants

Gene:TREM2

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
1–12 of 227 variants
651 papers
NM_018965.4
p.R47H
c.140G>A
213 papers
NM_018965.4
p.R62H
c.185G>A
145 papers
NM_018965.4
p.T66M
c.197C>T
115 papers
NM_018965.4
p.Q33*
c.97C>T
102 papers
NM_018965.4
p.H157Y
c.469C>T
95 papers
NM_018965.4
p.D87N
c.259G>A
90 papers
NM_018965.4
p.Y38C
c.113A>G
82 papers
NM_018965.4
p.T96K
c.287C>A
57 papers
NM_018965.4
p.L211P
c.632T>C
29 papers
NM_018965.4
p.V126G
c.377T>G
26 papers
NM_018965.4
p.R98W
c.292C>T
23 papers
NM_018965.4
p.D134G
c.401A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."