Varaico: Literature-Extracted Genetic Variants

CRBN

173 papers

RefSeq Summary

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and ...

Pfam Domains

LON_substr_bdgaa 80–317UCSCATP-dependent protease La (LON) substrate-binding domain

Yippee-Mis18aa 319–437UCSCYippee zinc-binding/DNA-binding /Mis18, centromere assembly

Gene Aliases

HGNC Name

cereblon

HGNC Previous Symbol

MRT2A

Papers

RefSeq ID

Protein change

DNA change

1–12 of 204 variants

27 papers

NM_016302.4

p.R419*

c.1255C>T

9 papers

NM_016302.4

p.V388I

c.1162G>A

8 papers

NM_016302.4

p.C391R

c.1171T>C

5 papers

NM_016302.4

p.R283K

c.848G>A

5 papers

NM_016302.4

p.P352S

c.1054C>T

4 papers

NM_016302.4

p.D249Y

c.745G>T

4 papers

NM_016302.4

p.E377V

c.1130A>T

4 papers

NM_016302.4

p.H397Y

c.1189C>T

4 papers

NM_016302.4

p.T425M

c.1274C>T

3 papers

NM_016302.4

p.E30K

c.88G>A

3 papers

NM_016302.4

p.T119A

c.355A>G

3 papers

NM_016302.4

p.L190F

c.570G>T